Allergic call dermatitis come pure henna Muhterem Polat MD, Meltem Dikilitaş MD, Pınar Öztaş MD Asc Prof, Nuran Allı MD Asc Prof Dermatology virtual Journal 15 (1): 15 Ankara Numune Education and also Research Hospital, room of very first Dermatology, Ankara, Turkey. Drmuhterempolat

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Henna is a naturally arising brown dye made from the leaves of the tree Lawsonia inermis. The active ingredient of henna is lawsone (2-hydroxy-1, 4-naphthoquinone). That is traditionally supplied in Islamic and Hindu societies as a hair coloring and as a dye for decorating the nails or making temporary skin tattoos. Actually, henna has a very low allergy potential. In most cases, allergy reactions not resulted in by henna, however by the chemical coloring additives that are included to henna mixtures. This additives include agents such together daiminotoluenes and diaminobenzenes. In this article, we report a situation of allergic call dermatitis native pure henna that is additionally used for the relief of rheumatic pain.


Henna (Lawsonia inermis) is component of the family Lythraceae, ideal known as a source of herbal dyes. It is traditionally offered in Islamic and also Hindu cultures as a hair coloring and also as a dye for decorating the nails or making short-lived skin tattoos. Allergic call dermatitis to pure henna is incredibly rare <1, 2>. We existing a instance of allergic call dermatitis come pure henna used for the relief the rheumatological share pain.

Case reportFigure 1
Figure 1. Contact dermatitis on the leg

A 30-year-old mrs was admitted to our outpatient clinic because of erythema and also edema on she leg that had appeared approximately one week after the applications of henna blended with vinegar. Dermatological examination revealed erythema and slight edema expanding from the upper component of the appropriate knee to the proximal part of the reduced leg (Fig. 1). Her past medical background was no contributory. The patient reported the she had added vinegar to natural powder henna and also applied this mixture over she knee. It to be left there for 6 hours in bespeak to relax the share pain.

Figure 2
Figure 2. Job test outcomes after 48 hrs (K: henna, S: vinegar, K+S: henna+vinegar)

A diagnosis of allergic call dermatitis come henna to be made and also the patient to be advised to apply betamethasone dipropionate 0.05 percent cream twice daily. Remission to be observed after 10 days. The patient was patch tested with the european Standard series including p-phenylenediamine (PPD), organic henna diluted through sterile saline solution in 1 percent concentration, natural henna blended with vinegar, and also vinegar only. Reactions were review at 48 and 72 hours. The patient proved a confident vesicular reaction to herbal henna (K in Fig. 2), probably because of delayed hypersensitivity, and a more powerful reaction to organic henna blended with vinegar (S-K in Fig. 2). There was no reaction in ~ the vinegar website (Fig. 2).


The use of henna dye is classic in Islamic countries. It has actually a spiritual and social definition <3>. In old times, henna was recommended together a remedy. The tree was used as a medication for jaundice, leprosy, smallpox, and skin complaints <4>. In Turkey, plants space widely supplied for countless indications. Henna is just one of these plants and is used specifically for mycotic infections and pruritus.

Despite its enhanced use, since of its low allerginicity, call dermatitis to henna seems to be rarely in individuals without work exposure <3>. The majority of instances of allergic call dermatitis to henna are linked with the applications of coloring agents (usually PPD) come produce much more intense coloration and also to mitigate fixation time <2>. Natural substances such together lemon oil, vinegar, and eucalyptus oil are added to acquire different shades <5>. Our patient provided vinegar to boost the impact of henna. Return there to be no reaction at the site of vinegar only, there was a more powerful reaction in ~ the website of pure henna mixed with vinegar compared to henna alone. Vinegar can have contributed a nonspecific irritant result or may cause a chemical adjust in the henna such the it is more allergenic.

Turkey is an Islamic country where many human being traditionally use henna for different purposes such as hand and also nail decoration and the dyeing the hair; it is likewise used to relax pain and pruritus and also to law infections. Hence, world should be aware of the potential side effects of henna and warnings about the risk of using henna space warranted.

Acknowledgement: us would prefer to thank MD Prof Meltem Önder (Gazi University college of Medicine, skiership Department) for her elegant aid in analyzing our patient and also preparing this manuscript.


1. Thami GP, Kaur S, Kanwar AJ Allergic call dermatitis to henna. Allergy 2001; 56: 1013-4. 2. Belhadjali H, Ghannouchi N, Amri Ch, et al call dermatitis come henna used as a hair dye call Dermatitis 2008; 58: 182. 3. Öztaş MO, Önder M, Öztaş P, Atahan Ç. Contact allergy to henna. J Eur Acad Dermatol Venereol 2001; 15: 91-2. 4. Kazandjieva J, Grozdev I, Tsankov N. Temporary henna tattoos Clinics in Dermatol 2007; 25: 383-7. 5. Nawaf A, Joshi A, Nour-Eldin O. Acute allergic call dermatitis due to para-phenylenediamine after short-lived henna painting.

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J Dermatol 2003; 30: 797-800.